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Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age

We encountered a 12‐year‐old boy with type 2 diabetes who was born small‐for‐gestational age. We described his clinical characteristics and a possible etiological factor for development of hyperglycemia. He developed well with sufficient nutrition and progressed to being overweight at 6 years‐of‐age...

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Autores principales: Kuwabara, Remi, Urakami, Tatsuhiko, Yoshida, Kei, Morioka, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477531/
https://www.ncbi.nlm.nih.gov/pubmed/32142215
http://dx.doi.org/10.1111/jdi.13246
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author Kuwabara, Remi
Urakami, Tatsuhiko
Yoshida, Kei
Morioka, Ichiro
author_facet Kuwabara, Remi
Urakami, Tatsuhiko
Yoshida, Kei
Morioka, Ichiro
author_sort Kuwabara, Remi
collection PubMed
description We encountered a 12‐year‐old boy with type 2 diabetes who was born small‐for‐gestational age. We described his clinical characteristics and a possible etiological factor for development of hyperglycemia. He developed well with sufficient nutrition and progressed to being overweight at 6 years‐of‐age as a result of a high‐calorie, high‐protein intake diet. He showed a diabetic pattern with a normal insulin response on an oral glucose tolerance test carried out with the urine glucose screening program at schools. He showed a large total fat area of 239.4 cm(2); in particular, his visceral fat area was 103.0 cm(2) with a high ratio of visceral fat area to subcutaneous fat area (0.76). The present case might show that insulin resistance, possibly as a result of accumulation of a great amount of visceral fat, might be attributed to the pathogenesis of type 2 diabetes in children born small‐for‐gestational age.
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spelling pubmed-74775312020-09-11 Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age Kuwabara, Remi Urakami, Tatsuhiko Yoshida, Kei Morioka, Ichiro J Diabetes Investig Articles We encountered a 12‐year‐old boy with type 2 diabetes who was born small‐for‐gestational age. We described his clinical characteristics and a possible etiological factor for development of hyperglycemia. He developed well with sufficient nutrition and progressed to being overweight at 6 years‐of‐age as a result of a high‐calorie, high‐protein intake diet. He showed a diabetic pattern with a normal insulin response on an oral glucose tolerance test carried out with the urine glucose screening program at schools. He showed a large total fat area of 239.4 cm(2); in particular, his visceral fat area was 103.0 cm(2) with a high ratio of visceral fat area to subcutaneous fat area (0.76). The present case might show that insulin resistance, possibly as a result of accumulation of a great amount of visceral fat, might be attributed to the pathogenesis of type 2 diabetes in children born small‐for‐gestational age. John Wiley and Sons Inc. 2020-03-26 2020-09 /pmc/articles/PMC7477531/ /pubmed/32142215 http://dx.doi.org/10.1111/jdi.13246 Text en © 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Articles
Kuwabara, Remi
Urakami, Tatsuhiko
Yoshida, Kei
Morioka, Ichiro
Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title_full Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title_fullStr Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title_full_unstemmed Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title_short Case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
title_sort case of type 2 diabetes possibly caused by excessive accumulation of visceral fat in a child born small‐for‐gestational age
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477531/
https://www.ncbi.nlm.nih.gov/pubmed/32142215
http://dx.doi.org/10.1111/jdi.13246
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