Human CD8(+) T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses

T cells recognizing cognate pMHC Ags become activated to elicit a myriad of cellular responses, such as target cell killing and the secretion of different cytokines, that collectively contribute to adaptive immunity. These effector responses have been hypothesized to exhibit different Ag dose and af...

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Detalles Bibliográficos
Autores principales: Abu-Shah, Enas, Trendel, Nicola, Kruger, Philipp, Nguyen, John, Pettmann, Johannes, Kutuzov, Mikhail, Dushek, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2020
Materias:
Antigen Recognition and Responses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477745/
https://www.ncbi.nlm.nih.gov/pubmed/32817332
http://dx.doi.org/10.4049/jimmunol.2000525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477745/
https://www.ncbi.nlm.nih.gov/pubmed/32817332
http://dx.doi.org/10.4049/jimmunol.2000525

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