Cargando…
Human CD8(+) T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses
T cells recognizing cognate pMHC Ags become activated to elicit a myriad of cellular responses, such as target cell killing and the secretion of different cytokines, that collectively contribute to adaptive immunity. These effector responses have been hypothesized to exhibit different Ag dose and af...
Autores principales: | Abu-Shah, Enas, Trendel, Nicola, Kruger, Philipp, Nguyen, John, Pettmann, Johannes, Kutuzov, Mikhail, Dushek, Omer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477745/ https://www.ncbi.nlm.nih.gov/pubmed/32817332 http://dx.doi.org/10.4049/jimmunol.2000525 |
Ejemplares similares
-
Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen
por: Choudhary, Alok, et al.
Publicado: (2018) -
Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals
por: Nielsen, Carolyn M., et al.
Publicado: (2015) -
Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
por: Rius, Cristina, et al.
Publicado: (2018) -
Systematic Determination of TCR–Antigen and Peptide–MHC Binding Kinetics among Field Variants of a Theileria parva Polymorphic CTL Epitope
por: Svitek, Nicholas, et al.
Publicado: (2022) -
Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival
por: Ackermann, Jochen A., et al.
Publicado: (2015)