Cargando…
CD226 Attenuates Treg Proliferation via Akt and Erk Signaling in an EAE Model
Cluster of differentiation 226 (CD226) molecules play a crucial role in the activation of effector CD4(+) T cells during the immune response process, but a cell-intrinsic function of CD226 in CD4(+) T subsets is not clear. In this study, we showed that Cd226(−/−) mice were resistant to myelin oligod...
Autores principales: | Wang, Ning, Yi, Hongyu, Fang, Liang, Jin, Jingyi, Ma, Qianli, Shen, Yuting, Li, Juan, Liang, Shuang, Xiong, Jie, Li, Zhuo, Zeng, Hanyu, Jiang, Fengliang, Jin, Boquan, Chen, Lihua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478170/ https://www.ncbi.nlm.nih.gov/pubmed/32983109 http://dx.doi.org/10.3389/fimmu.2020.01883 |
Ejemplares similares
-
CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4(+) T cell differentiation
por: Zhang, Rong, et al.
Publicado: (2016) -
CD226 deficiency improves cognitive functions and ameliorates anxiety‐like behaviors in mice
por: Fang, Liang, et al.
Publicado: (2017) -
Expression of CD226 is upregulated on Tr1 cells from neuromyelitis optica spectrum disorder patients
por: Chen, Ping, et al.
Publicado: (2022) -
Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients
por: Xu, Zhuwei, et al.
Publicado: (2009) -
Exosomes with FOXP3 from gene-modified dendritic cells ameliorate the development of EAE by regulating the balance of Th/Treg
por: Jia, Zhen, et al.
Publicado: (2022)