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Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma
Tc-99m methylene diphosphonate bone scintigraphy (bone scan) is a highly sensitive technique for the evaluation of osseous pathology. However, the nonspecificity of the method can present diagnostic challenges in differentiating benign from malignant processes. Often, Paget’s disease and osseous met...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478306/ https://www.ncbi.nlm.nih.gov/pubmed/32939203 http://dx.doi.org/10.4103/wjnm.WJNM_63_19 |
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author | Devita, Robert Chagarlamudi, Kaushik Kardan, Arash |
author_facet | Devita, Robert Chagarlamudi, Kaushik Kardan, Arash |
author_sort | Devita, Robert |
collection | PubMed |
description | Tc-99m methylene diphosphonate bone scintigraphy (bone scan) is a highly sensitive technique for the evaluation of osseous pathology. However, the nonspecificity of the method can present diagnostic challenges in differentiating benign from malignant processes. Often, Paget’s disease and osseous metastasis can coexist in elderly patients. Therefore, it is important to accurately distinguish the two pathologies, as each has a different prognosis and impacts clinical management. Obtaining the appropriate clinical diagnosis often involves a combination of laboratory, radiographic, and clinical data. We present a case of newly diagnosed prostatic carcinoma presenting with synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease. |
format | Online Article Text |
id | pubmed-7478306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-74783062020-09-15 Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma Devita, Robert Chagarlamudi, Kaushik Kardan, Arash World J Nucl Med Case Report Tc-99m methylene diphosphonate bone scintigraphy (bone scan) is a highly sensitive technique for the evaluation of osseous pathology. However, the nonspecificity of the method can present diagnostic challenges in differentiating benign from malignant processes. Often, Paget’s disease and osseous metastasis can coexist in elderly patients. Therefore, it is important to accurately distinguish the two pathologies, as each has a different prognosis and impacts clinical management. Obtaining the appropriate clinical diagnosis often involves a combination of laboratory, radiographic, and clinical data. We present a case of newly diagnosed prostatic carcinoma presenting with synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease. Wolters Kluwer - Medknow 2020-01-17 /pmc/articles/PMC7478306/ /pubmed/32939203 http://dx.doi.org/10.4103/wjnm.WJNM_63_19 Text en Copyright: © 2020 World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Devita, Robert Chagarlamudi, Kaushik Kardan, Arash Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title | Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title_full | Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title_fullStr | Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title_full_unstemmed | Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title_short | Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget’s disease in a case of newly diagnosed prostatic carcinoma |
title_sort | synchronous osseous metastasis, degenerative changes, and incidental multifocal paget’s disease in a case of newly diagnosed prostatic carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478306/ https://www.ncbi.nlm.nih.gov/pubmed/32939203 http://dx.doi.org/10.4103/wjnm.WJNM_63_19 |
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