Cargando…

FAM46B Promotes Apoptosis and Inhibits Glycolysis of Prostate Cancer Through Inhibition of the MYC-LDHA Axis

OBJECTIVE: Increased dependence on glycolysis is a known element of cancer. This study was designed to examine critical glycolysis components including transcription factor MYC and its downstream target lactate dehydrogenase A (LDHA), potential upstream regulators of glycolysis such as family with s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Tao, Ye, Xuxiao, Yan, Dongliang, Deng, Chao, Li, Zuowei, Tian, Binqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478375/ https://www.ncbi.nlm.nih.gov/pubmed/32943883 http://dx.doi.org/10.2147/OTT.S258724

Ejemplares similares

FAM46B inhibits cell proliferation and cell cycle progression in prostate cancer through ubiquitination of β-catenin
por: Liang, Tao, et al.
Publicado: (2018)

The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer
por: He, Tian-Lin, et al.
Publicado: (2015)

Down-Regulation of Nfatc1 Suppresses Proliferation, Migration, Invasion, and Warburg Effect in Prostate Cancer Cells
por: Liu, Yuanyuan, et al.
Publicado: (2019)

Inhibition of KDM4C/c‐Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism
por: Lin, Ching‐Yu, et al.
Publicado: (2022)

MYC Promotes LDHA Expression through MicroRNA-122-5p to Potentiate Glycolysis in Hepatocellular Carcinoma
por: Wang, Xiaofei, et al.
Publicado: (2022)

Inhibition of LDHA suppresses tumor progression in prostate cancer
por: Xian, Zhi-Yong, et al.
Publicado: (2015)

The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer
por: Fang, Zhixiong, et al.
Publicado: (2017)

Hypoxia‐induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression
por: Wang, Xiao‐Hong, et al.
Publicado: (2021)

USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis
por: Liu, Shuguang, et al.
Publicado: (2023)

FAM46C inhibits cell proliferation and cell cycle progression and promotes apoptosis through PTEN/AKT signaling pathway and is associated with chemosensitivity in prostate cancer
por: Ma, Libin, et al.
Publicado: (2020)

STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis
por: Huo, Nan, et al.
Publicado: (2021)

Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis
por: Guan, Hua, et al.
Publicado: (2021)

Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis
por: Gao, Mingjun, et al.
Publicado: (2021)

Curcumin Antagonizes Glucose Fluctuation-Induced Renal Injury by Inhibiting Aerobic Glycolysis via the miR-489/LDHA Pathway
por: Fu, Xiaomei, et al.
Publicado: (2021)

MiR-638 Repressed Vascular Smooth Muscle Cell Glycolysis by Targeting LDHA
por: Chen, Shiyuan, et al.
Publicado: (2019)

Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold
por: Liu, Shun, et al.
Publicado: (2023)

FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy
por: Mancino, Marilena, et al.
Publicado: (2023)

Repair of urethral defects by an adipose mesenchymal stem cell-porous silk fibroin material
por: Tian, Binqiang, et al.
Publicado: (2018)

Novel Peptide Inhibitors for Lactate Dehydrogenase A (LDHA): A Survey to Inhibit LDHA Activity via Disruption of Protein-Protein Interaction
por: Jafary, Farzaneh, et al.
Publicado: (2019)

CDKN3 Overcomes Bladder Cancer Cisplatin Resistance via LDHA-Dependent Glycolysis Reprogramming
por: Li, Mengxuan, et al.
Publicado: (2022)

LDHA Suppression Altering Metabolism Inhibits Tumor Progress by an Organic Arsenical
por: Liu, Yu-Jiao, et al.
Publicado: (2019)

Ginsenoside Rh2 Inhibits Glycolysis through the STAT3/c-MYC Axis in Non-Small-Cell Lung Cancer
por: Sun, Xiaodan, et al.
Publicado: (2021)

Pancancer Analysis of Neurovascular-Related NRP Family Genes as Potential Prognostic Biomarkers of Bladder Urothelial Carcinoma
por: Deng, Chao, et al.
Publicado: (2021)

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2
por: Wang, Chunqing, et al.
Publicado: (2020)

PCK1 Regulates Glycolysis and Tumor Progression in Clear Cell Renal Cell Carcinoma Through LDHA
por: Shi, Liang, et al.
Publicado: (2020)

LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial–Mesenchymal Transition
por: Cai, Hongshi, et al.
Publicado: (2019)

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer
por: Niu, Weihong, et al.
Publicado: (2018)

Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells
por: Zhang, Wenjing, et al.
Publicado: (2022)

Effect of LDHA Inhibition on TNF-α-Induced Cell Migration in Esophageal Cancers
por: Forkasiewicz, Agata, et al.
Publicado: (2022)

FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma
por: Herrero, Ana Belén, et al.
Publicado: (2020)

FAM46C/TENT5C functions as a tumor suppressor through inhibition of Plk4 activity
por: Kazazian, Karineh, et al.
Publicado: (2020)

TOP1MT deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis
por: Wang, Hongqiang, et al.
Publicado: (2017)

Circular RNA circVAMP3 promotes aerobic glycolysis and proliferation by regulating LDHA in renal cell carcinoma
por: Li, Jun, et al.
Publicado: (2022)

Circular RNA, circular RARS, promotes aerobic glycolysis of non‐small‐cell lung cancer by binding with LDHA
por: Li, Haoran, et al.
Publicado: (2023)

Long non-coding RNA CCHE1 modulates LDHA-mediated glycolysis and confers chemoresistance to melanoma cells
por: Ding, Zhi, et al.
Publicado: (2023)

Dioscin Inhibited Glycolysis and Induced Cell Apoptosis in Colorectal Cancer via Promoting c-myc Ubiquitination and Subsequent Hexokinase-2 Suppression
por: Wu, Zhenqian, et al.
Publicado: (2020)

APOL3-LDHA axis related immunity activation and cancer ferroptosis induction
por: Feng, Yuzhao, et al.
Publicado: (2023)

FOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis
por: Wu, Changhao, et al.
Publicado: (2023)

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells
por: Urbańska, Kaja, et al.
Publicado: (2019)

N(6)-methyladenosine modification of REG1α facilitates colorectal cancer progression via β-catenin/MYC/LDHA axis mediated glycolytic reprogramming
por: Zhou, Mingxia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jtjq4128u82rdbn2p74kbt9h14