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Prevention of bone infection after open fracture using a chitosan with ciprofloxacin implant in animal model

PURPOSE: To evaluate different concentrations of ciprofloxacin to prevent infection after open fracture contaminated with S. aureus in rats using absorbable local delivery system. METHODS: Fifty-two Wistar rats were assigned to six groups. After 4 weeks, all animals underwent 99mTc-ceftizoxima scint...

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Detalles Bibliográficos
Autores principales: Kobata, Silvia Iovine, Teixeira, Luiz Eduardo Moreira, Fernandes, Simone Odilia Antunes, Faraco, André Augusto Gomes, Vidigal, Paula Vieira Teixeira, de Araújo, Ivana Duval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478494/
https://www.ncbi.nlm.nih.gov/pubmed/32901680
http://dx.doi.org/10.1590/s0102-865020200080000003

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