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A Case Report on Dengue Encephalitis With Optic Neuropathy
The dengue virus is a type of Flavivirus, responsible for causing dengue fever. It mostly prevails in tropical and subtropical countries, with Southeast Asia reporting the greatest disease burden. The virus can affect a multitude of organ systems and the disease spectrum varies from a mild flu-like...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478582/ https://www.ncbi.nlm.nih.gov/pubmed/32923198 http://dx.doi.org/10.7759/cureus.9592 |
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author | Khan, Nawal Bhatti, Jamil M |
author_facet | Khan, Nawal Bhatti, Jamil M |
author_sort | Khan, Nawal |
collection | PubMed |
description | The dengue virus is a type of Flavivirus, responsible for causing dengue fever. It mostly prevails in tropical and subtropical countries, with Southeast Asia reporting the greatest disease burden. The virus can affect a multitude of organ systems and the disease spectrum varies from a mild flu-like illness to severe dengue hemorrhagic fever or dengue shock syndrome. Two serotypes, DENV-2 and DENV-3, have been most frequently associated with neurological complications. We report a case of a 19-year-old male presented with signs and symptoms of encephalitis and optic neuropathy, following a diagnosis of dengue fever. Our diagnosis was supported by findings from brain MRI, electroencephalogram, fundoscopy, and a visual evoked potential test. A high-dose intravenous steroid therapy was given in pulses, which resulted in complete visual and neurological recovery. Dengue fever can present with atypical findings due to its propensity to affect multiple organ systems throughout the body. Neurological involvement is not uncommon and hence, clinicians should be aware of such systemic manifestations in order to diagnose promptly. Effective and timely treatment can reduce associated morbidity and result in complete recovery. |
format | Online Article Text |
id | pubmed-7478582 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-74785822020-09-11 A Case Report on Dengue Encephalitis With Optic Neuropathy Khan, Nawal Bhatti, Jamil M Cureus Neurology The dengue virus is a type of Flavivirus, responsible for causing dengue fever. It mostly prevails in tropical and subtropical countries, with Southeast Asia reporting the greatest disease burden. The virus can affect a multitude of organ systems and the disease spectrum varies from a mild flu-like illness to severe dengue hemorrhagic fever or dengue shock syndrome. Two serotypes, DENV-2 and DENV-3, have been most frequently associated with neurological complications. We report a case of a 19-year-old male presented with signs and symptoms of encephalitis and optic neuropathy, following a diagnosis of dengue fever. Our diagnosis was supported by findings from brain MRI, electroencephalogram, fundoscopy, and a visual evoked potential test. A high-dose intravenous steroid therapy was given in pulses, which resulted in complete visual and neurological recovery. Dengue fever can present with atypical findings due to its propensity to affect multiple organ systems throughout the body. Neurological involvement is not uncommon and hence, clinicians should be aware of such systemic manifestations in order to diagnose promptly. Effective and timely treatment can reduce associated morbidity and result in complete recovery. Cureus 2020-08-06 /pmc/articles/PMC7478582/ /pubmed/32923198 http://dx.doi.org/10.7759/cureus.9592 Text en Copyright © 2020, Khan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Neurology Khan, Nawal Bhatti, Jamil M A Case Report on Dengue Encephalitis With Optic Neuropathy |
title | A Case Report on Dengue Encephalitis With Optic Neuropathy |
title_full | A Case Report on Dengue Encephalitis With Optic Neuropathy |
title_fullStr | A Case Report on Dengue Encephalitis With Optic Neuropathy |
title_full_unstemmed | A Case Report on Dengue Encephalitis With Optic Neuropathy |
title_short | A Case Report on Dengue Encephalitis With Optic Neuropathy |
title_sort | case report on dengue encephalitis with optic neuropathy |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478582/ https://www.ncbi.nlm.nih.gov/pubmed/32923198 http://dx.doi.org/10.7759/cureus.9592 |
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