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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age

Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different patient populations. The mechanisms behind these host differences are still unclear. Here, we examined host response gene expression across i...

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Detalles Bibliográficos
Autores principales: Lieberman, Nicole A. P., Peddu, Vikas, Xie, Hong, Shrestha, Lasata, Huang, Meei-Li, Mears, Megan C., Cajimat, Maria N., Bente, Dennis A., Shi, Pei-Yong, Bovier, Francesca, Roychoudhury, Pavitra, Jerome, Keith R., Moscona, Anne, Porotto, Matteo, Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478592/
https://www.ncbi.nlm.nih.gov/pubmed/32898168
http://dx.doi.org/10.1371/journal.pbio.3000849