Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients

Since SARS-CoV-2-based disease (COVID-19) spreads as a pandemic, the necessity of a highly sensitive molecular diagnosis that can drastically reduce false negatives reverse transcription PCR (rtPCR) results, raises as a major clinical need. Here we evaluated the performance of a ddPCR-based assay to...

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Detalles Bibliográficos
Autores principales: Alteri, Claudia, Cento, Valeria, Antonello, Maria, Colagrossi, Luna, Merli, Marco, Ughi, Nicola, Renica, Silvia, Matarazzo, Elisa, Di Ruscio, Federica, Tartaglione, Livia, Colombo, Jacopo, Grimaldi, Chiara, Carta, Stefania, Nava, Alice, Costabile, Valentino, Baiguera, Chiara, Campisi, Daniela, Fanti, Diana, Vismara, Chiara, Fumagalli, Roberto, Scaglione, Francesco, Epis, Oscar Massimiliano, Puoti, Massimo, Perno, Carlo Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478621/
https://www.ncbi.nlm.nih.gov/pubmed/32898153
http://dx.doi.org/10.1371/journal.pone.0236311

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