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Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study

In China, there is a significant lack of awareness of diabetes and its complications. Screening of diabetic retinopathy has important for early detection, prevention, and treatment. This large, cross-sectional study aimed to characterize the demographic, physical, serological, and ocular characteris...

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Autores principales: Yin, Li, Zhang, Delong, Ren, Qian, Su, Xian, Sun, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478682/
https://www.ncbi.nlm.nih.gov/pubmed/32118727
http://dx.doi.org/10.1097/MD.0000000000019236
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author Yin, Li
Zhang, Delong
Ren, Qian
Su, Xian
Sun, Zhaohui
author_facet Yin, Li
Zhang, Delong
Ren, Qian
Su, Xian
Sun, Zhaohui
author_sort Yin, Li
collection PubMed
description In China, there is a significant lack of awareness of diabetes and its complications. Screening of diabetic retinopathy has important for early detection, prevention, and treatment. This large, cross-sectional study aimed to characterize the demographic, physical, serological, and ocular characteristics of subjects with diabetes mellitus in Shijiazhuang, China. It also aimed to associate these characteristics with the presence of diabetic retinopathy. From May 2, 2018 to August 25, 2019, under diabetes care program, the diabetic patients (n = 1008) were subjected to standardized questionnaires to collect demographical characteristics. Also, telescreens and laboratory tests were performed for the enrolled patients. Multivariate logistic regression analysis was used to evaluate factors associated with diabetic retinopathy. Forty percent of diabetics in its population had some form of diabetic retinopathy. Diabetic retinopathic patients were likely to be elder (P = .0003), men (P = .018), hypertensive (P < .0001), and had high body mass index (P < .0001), metabolic abnormalities, and longer duration of diabetes (P < .0001). Higher intraocular pressure (P = .0008), fasting blood glucose (P < .0001), serum total cholesterol (P < .0001), serum triglyceride (P = .0006), % glycated hemoglobin (HbA1c) (P < .0001), and disc asymmetry including cup–disc ratio (P = .041) reported in patients with diabetic retinopathy. Age (P = .049), male sex (P = .048), hypertension (P = .048), duration of diabetes (P = .012), diabetic neuropathy (P = .048), diabetic nephropathy (P = .048), diabetic foot ulcer (P = .041), foot amputation (P = .042), fasting blood glucose (P = .022), serum total cholesterol (P = .028), serum triglyceride (P = .035), and HbA1c (P = .042) were associated with diabetic retinopathy. Diabetic retinopathy was the most common ocular fundus disease in diabetic patients. Also, aging, the other comorbidities, and metabolic syndrome are associated with diabetic retinopathy. Level of Evidence: III.
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spelling pubmed-74786822020-09-24 Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study Yin, Li Zhang, Delong Ren, Qian Su, Xian Sun, Zhaohui Medicine (Baltimore) 4400 In China, there is a significant lack of awareness of diabetes and its complications. Screening of diabetic retinopathy has important for early detection, prevention, and treatment. This large, cross-sectional study aimed to characterize the demographic, physical, serological, and ocular characteristics of subjects with diabetes mellitus in Shijiazhuang, China. It also aimed to associate these characteristics with the presence of diabetic retinopathy. From May 2, 2018 to August 25, 2019, under diabetes care program, the diabetic patients (n = 1008) were subjected to standardized questionnaires to collect demographical characteristics. Also, telescreens and laboratory tests were performed for the enrolled patients. Multivariate logistic regression analysis was used to evaluate factors associated with diabetic retinopathy. Forty percent of diabetics in its population had some form of diabetic retinopathy. Diabetic retinopathic patients were likely to be elder (P = .0003), men (P = .018), hypertensive (P < .0001), and had high body mass index (P < .0001), metabolic abnormalities, and longer duration of diabetes (P < .0001). Higher intraocular pressure (P = .0008), fasting blood glucose (P < .0001), serum total cholesterol (P < .0001), serum triglyceride (P = .0006), % glycated hemoglobin (HbA1c) (P < .0001), and disc asymmetry including cup–disc ratio (P = .041) reported in patients with diabetic retinopathy. Age (P = .049), male sex (P = .048), hypertension (P = .048), duration of diabetes (P = .012), diabetic neuropathy (P = .048), diabetic nephropathy (P = .048), diabetic foot ulcer (P = .041), foot amputation (P = .042), fasting blood glucose (P = .022), serum total cholesterol (P = .028), serum triglyceride (P = .035), and HbA1c (P = .042) were associated with diabetic retinopathy. Diabetic retinopathy was the most common ocular fundus disease in diabetic patients. Also, aging, the other comorbidities, and metabolic syndrome are associated with diabetic retinopathy. Level of Evidence: III. Wolters Kluwer Health 2020-02-28 /pmc/articles/PMC7478682/ /pubmed/32118727 http://dx.doi.org/10.1097/MD.0000000000019236 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 4400
Yin, Li
Zhang, Delong
Ren, Qian
Su, Xian
Sun, Zhaohui
Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title_full Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title_fullStr Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title_full_unstemmed Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title_short Prevalence and risk factors of diabetic retinopathy in diabetic patients: A community based cross-sectional study
title_sort prevalence and risk factors of diabetic retinopathy in diabetic patients: a community based cross-sectional study
topic 4400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478682/
https://www.ncbi.nlm.nih.gov/pubmed/32118727
http://dx.doi.org/10.1097/MD.0000000000019236
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