A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis

Pulmonary fibrosis is a chronic progressive interstitial lung disease characterized by repetitive cycles of epithelial cell injury and dysregulated repair. Although most cases of pulmonary fibrosis are idiopathic, a detailed history that includes medications, comorbidities, tobacco use, environmenta...

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Autores principales: Drekolias, Dimitrios, Gadela, Naga Vaishnavi, Krupka, Philip, Broess, Jennifer, Jacob, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478690/
https://www.ncbi.nlm.nih.gov/pubmed/32923218
http://dx.doi.org/10.7759/cureus.9617
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author Drekolias, Dimitrios
Gadela, Naga Vaishnavi
Krupka, Philip
Broess, Jennifer
Jacob, Jason
author_facet Drekolias, Dimitrios
Gadela, Naga Vaishnavi
Krupka, Philip
Broess, Jennifer
Jacob, Jason
author_sort Drekolias, Dimitrios
collection PubMed
description Pulmonary fibrosis is a chronic progressive interstitial lung disease characterized by repetitive cycles of epithelial cell injury and dysregulated repair. Although most cases of pulmonary fibrosis are idiopathic, a detailed history that includes medications, comorbidities, tobacco use, environmental exposures, and family history should be taken to rule out secondary etiology. We present a case of flavocoxid-induced pulmonary toxicity which progressed from hypersensitivity pneumonitis to pulmonary fibrosis even after discontinuation of the offending drug.
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spelling pubmed-74786902020-09-11 A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis Drekolias, Dimitrios Gadela, Naga Vaishnavi Krupka, Philip Broess, Jennifer Jacob, Jason Cureus Internal Medicine Pulmonary fibrosis is a chronic progressive interstitial lung disease characterized by repetitive cycles of epithelial cell injury and dysregulated repair. Although most cases of pulmonary fibrosis are idiopathic, a detailed history that includes medications, comorbidities, tobacco use, environmental exposures, and family history should be taken to rule out secondary etiology. We present a case of flavocoxid-induced pulmonary toxicity which progressed from hypersensitivity pneumonitis to pulmonary fibrosis even after discontinuation of the offending drug. Cureus 2020-08-08 /pmc/articles/PMC7478690/ /pubmed/32923218 http://dx.doi.org/10.7759/cureus.9617 Text en Copyright © 2020, Drekolias et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Drekolias, Dimitrios
Gadela, Naga Vaishnavi
Krupka, Philip
Broess, Jennifer
Jacob, Jason
A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title_full A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title_fullStr A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title_full_unstemmed A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title_short A Rare Case of Flavocoxid-Induced Pulmonary Fibrosis
title_sort rare case of flavocoxid-induced pulmonary fibrosis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478690/
https://www.ncbi.nlm.nih.gov/pubmed/32923218
http://dx.doi.org/10.7759/cureus.9617
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