Cargando…

Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing

Antigen uptake and presentation by naive and germinal center (GC) B cells are different, with the former expressing even low-affinity BCRs efficiently capture and present sufficient antigen to T cells, whereas the latter do so more efficiently after acquiring high-affinity BCRs. We show here that an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xin, Gong, Liying, Meli, Alexandre P., Karo-Atar, Danielle, Sun, Weili, Zou, Yongrui, King, Irah L., Gu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478728/ https://www.ncbi.nlm.nih.gov/pubmed/32584413 http://dx.doi.org/10.1084/jem.20191537

Ejemplares similares

Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells
por: Tong, Haijun, et al.
Publicado: (2021)

Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency
por: Huemer, Martina, et al.
Publicado: (2016)

A novel CBL-B(flox/flox) mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells
por: Goetz, Benjamin, et al.
Publicado: (2016)

Targeting Cbl-b in cancer immunotherapy
por: Augustin, Ryan C., et al.
Publicado: (2023)

Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
por: Pedersen, Anna-Kathrine, et al.
Publicado: (2021)

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy
por: An, Wei, et al.
Publicado: (2015)

Calcineurin B-Like Proteins CBL4 and CBL10 Mediate Two Independent Salt Tolerance Pathways in Arabidopsis
por: Yang, Yang, et al.
Publicado: (2019)

Knockout of c-Cbl/Cbl-b slows c-Met trafficking resulting in enhanced signaling in corneal epithelial cells
por: Tarvestad-Laise, Kate, et al.
Publicado: (2023)

Isoflurane decreases interleukin-2 production by increasing c-Cbl and Cbl-b expression in rat peripheral blood mononuclear cells
por: Choi, Ji Won, et al.
Publicado: (2018)

c-Cbl、Cbl-b和EGFR在非小细胞肺癌中的表达及其预后价值
Publicado: (2011)

VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease
por: An, Wei, et al.
Publicado: (2016)

Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance
por: Abe, Tomoki, et al.
Publicado: (2017)

Cbl-b deficiency prevents functional but not phenotypic T cell anergy
por: Nguyen, Trang T.T., et al.
Publicado: (2021)

Abnormal B-Cell Maturation and Increased Transitional B Cells in CBL Syndrome
por: Saettini, Francesco, et al.
Publicado: (2022)

Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
Publicado: (1996)

SLAM family receptors control pro-survival effectors in germinal center B cells to promote humoral immunity
por: Zhong, Ming-Chao, et al.
Publicado: (2020)

Spontaneous tumor rejection by cbl-b–deficient CD8(+) T cells
por: Loeser, Stefanie, et al.
Publicado: (2007)

Releasing the Brake: Targeting Cbl-b to Enhance Lymphocyte Effector Functions
por: Wallner, Stephanie, et al.
Publicado: (2012)

The Role of the E3 Ligase Cbl-B in Murine Dendritic Cells
por: Wallner, Stephanie, et al.
Publicado: (2013)

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b
por: Lutz-Nicoladoni, Christina, et al.
Publicado: (2015)

Expression and Comparison of Cbl-b in Lung Squamous Cell Carcinoma and Adenocarcinoma
por: Li, Peng, et al.
Publicado: (2018)

Mutations of c-Cbl in myeloid malignancies
por: Katzav, Shulamit, et al.
Publicado: (2015)

Recruitment of Cbl-b to B Cell Antigen Receptor Couples Antigen Recognition to Toll-Like Receptor 9 Activation in Late Endosomes
por: Veselits, Margaret, et al.
Publicado: (2014)

H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b
por: Vennin, Constance, et al.
Publicado: (2015)

Ablation of Cbl-b and c-Cbl in dendritic cells causes spontaneous liver cirrhosis via altering multiple properties of CD103(+) cDC1s
por: Xu, Fei, et al.
Publicado: (2022)

Cbl-b Negatively Regulates B Cell Antigen Receptor Signaling in Mature B Cells through Ubiquitination of the Tyrosine Kinase Syk
por: Sohn, Hae Won, et al.
Publicado: (2003)

E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
por: Ahmed, Syed Feroj, et al.
Publicado: (2021)

Cbl-b silenced human NK cells respond stronger to cytokine stimulation
por: Lametschwandtner, Guenther, et al.
Publicado: (2015)

Cbl-b predicts postoperative survival in patients with resectable pancreatic ductal adenocarcinoma
por: Dong, Qian, et al.
Publicado: (2017)

Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b
por: Kwon, Ji Hye, et al.
Publicado: (2019)

Regulation of EGFR Endocytosis by CBL During Mitosis
por: Wee, Ping, et al.
Publicado: (2018)

Ectopic Expression of SjCBL1, Calcineurin B-Like 1 Gene From Sedirea japonica, Rescues the Salt and Osmotic Stress Hypersensitivity in Arabidopsis cbl1 Mutant
por: Cho, Joo Hyuk, et al.
Publicado: (2018)

Helminth-mediated disease tolerance in TB: A role for microbiota?
por: Karo-Atar, Danielle, et al.
Publicado: (2021)

Thermolability of mutant MMACHC protein in the vitamin B12-responsive cblC disorder
por: Froese, D.S., et al.
Publicado: (2010)

Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma
por: Carson, William F., et al.
Publicado: (2015)

Development of a personalized cellular ex-vivo cbl-b silencing cancer immunotherapy
por: Lametschwandtner, Guenther, et al.
Publicado: (2014)

Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b
por: Peer, Sebastian, et al.
Publicado: (2018)

The E3 Ubiquitin Ligase Cbl-b Predicts Favorable Prognosis in Breast Cancer
por: Liu, Xiuming, et al.
Publicado: (2020)

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana
por: Jiang, Wei, et al.
Publicado: (2021)

Cbl-b Positively Regulates Btk-mediated Activation of Phospholipase C-γ2 in B Cells
por: Yasuda, Tomoharu, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_1pjq0cmt3p46p4nvv5cj7vn6qm