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Distinct functions of tissue-resident and circulating memory Th2 cells in allergic airway disease

Memory CD4(+) T helper type 2 (Th2) cells drive allergic asthma, yet the mechanisms whereby tissue-resident memory Th2 (Th2 Trm) cells and circulating memory Th2 cells collaborate in vivo remain unclear. Using a house dust mite (HDM) model of allergic asthma and parabiosis, we demonstrate that Th2 T...

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Detalles Bibliográficos
Autores principales:	Rahimi, Rod A., Nepal, Keshav, Cetinbas, Murat, Sadreyev, Ruslan I., Luster, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478729/ https://www.ncbi.nlm.nih.gov/pubmed/32579670 http://dx.doi.org/10.1084/jem.20190865

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