Cargando…
Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes
The human liver contains specialized subsets of mononuclear phagocytes (MNPs) and T cells, but whether these have definitive features of tissue residence (long-term retention, lack of egress) and/or can be replenished from the circulation remains unclear. Here we addressed these questions using HLA-...
Autores principales: | Pallett, Laura J., Burton, Alice R., Amin, Oliver E., Rodriguez-Tajes, Sergio, Patel, Amit A., Zakeri, Nekisa, Jeffery-Smith, Anna, Swadling, Leo, Schmidt, Nathalie M., Baiges, Anna, Gander, Amir, Yu, Dominic, Nasralla, David, Froghi, Farid, Iype, Satheesh, Davidson, Brian R., Thorburn, Douglas, Yona, Simon, Forns, Xavier, Maini, Mala K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478732/ https://www.ncbi.nlm.nih.gov/pubmed/32602903 http://dx.doi.org/10.1084/jem.20200050 |
Ejemplares similares
-
Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma
por: Zakeri, Nekisa, et al.
Publicado: (2022) -
Human Liver Memory CD8(+) T Cells Use Autophagy for Tissue Residence
por: Swadling, Leo, et al.
Publicado: (2020) -
Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry
por: Kucykowicz, Stephanie, et al.
Publicado: (2022) -
Eomes(hi) NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation
por: Cuff, Antonia O., et al.
Publicado: (2016) -
Can T Cells Abort SARS-CoV-2 and Other Viral Infections?
por: Swadling, Leo, et al.
Publicado: (2023)