Membrane budding is a major mechanism of in vivo platelet biogenesis

How platelets are produced by megakaryocytes in vivo remains controversial despite more than a century of investigation. Megakaryocytes readily produce proplatelet structures in vitro; however, visualization of platelet release from proplatelets in vivo has remained elusive. We show that within the...

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Detalles Bibliográficos
Autores principales: Potts, Kathryn S., Farley, Alison, Dawson, Caleb A., Rimes, Joel, Biben, Christine, de Graaf, Carolyn, Potts, Margaret A., Stonehouse, Olivia J., Carmagnac, Amandine, Gangatirkar, Pradnya, Josefsson, Emma C., Anttila, Casey, Amann-Zalcenstein, Daniela, Naik, Shalin, Alexander, Warren S., Hilton, Douglas J., Hawkins, Edwin D., Taoudi, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478734/
https://www.ncbi.nlm.nih.gov/pubmed/32706855
http://dx.doi.org/10.1084/jem.20191206

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