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IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors
An important comorbidity of chronic inflammation is anemia, which may be related to dysregulated activity of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). Among HSPCs, we found that the receptor for IL-33, ST2, is expressed preferentially and highly on erythroid progenitor...
Autores principales: | Swann, James W., Koneva, Lada A., Regan-Komito, Daniel, Sansom, Stephen N., Powrie, Fiona, Griseri, Thibault |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478740/ https://www.ncbi.nlm.nih.gov/pubmed/32520308 http://dx.doi.org/10.1084/jem.20200164 |
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