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Phyllodes Tumors of the Breast: A Literature Review

Phyllodes tumors (PTs) of the breast are considered a rare fibroepithelial neoplasms of the breast and are considered a challenging for both pathologists and surgeons. The World Health Organization (WHO) has classified PTs histologically as benign, borderline, and malignant. PTs can be detected in a...

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Autor principal: Rayzah, Musaed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478785/
https://www.ncbi.nlm.nih.gov/pubmed/32923300
http://dx.doi.org/10.7759/cureus.10288
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author Rayzah, Musaed
author_facet Rayzah, Musaed
author_sort Rayzah, Musaed
collection PubMed
description Phyllodes tumors (PTs) of the breast are considered a rare fibroepithelial neoplasms of the breast and are considered a challenging for both pathologists and surgeons. The World Health Organization (WHO) has classified PTs histologically as benign, borderline, and malignant. PTs can be detected in all ages; however, the median age of presentation is 45 years. PTs can mimic fibroadenoma in clinical presentations. Breast imaging is also similar to fibroadenomas. Cytological diagnosis of PTs by biopsy is usually unreliable. However, a core needle biopsy is superior to fine-needle aspiration. Surgery is considered the mainstay treatment for PTs of the breast with a goal of achieving negative margins. Adjuvant chemotherapy and radiation therapy use for malignant PTs are controversial.
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spelling pubmed-74787852020-09-11 Phyllodes Tumors of the Breast: A Literature Review Rayzah, Musaed Cureus General Surgery Phyllodes tumors (PTs) of the breast are considered a rare fibroepithelial neoplasms of the breast and are considered a challenging for both pathologists and surgeons. The World Health Organization (WHO) has classified PTs histologically as benign, borderline, and malignant. PTs can be detected in all ages; however, the median age of presentation is 45 years. PTs can mimic fibroadenoma in clinical presentations. Breast imaging is also similar to fibroadenomas. Cytological diagnosis of PTs by biopsy is usually unreliable. However, a core needle biopsy is superior to fine-needle aspiration. Surgery is considered the mainstay treatment for PTs of the breast with a goal of achieving negative margins. Adjuvant chemotherapy and radiation therapy use for malignant PTs are controversial. Cureus 2020-09-07 /pmc/articles/PMC7478785/ /pubmed/32923300 http://dx.doi.org/10.7759/cureus.10288 Text en Copyright © 2020, Rayzah et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Rayzah, Musaed
Phyllodes Tumors of the Breast: A Literature Review
title Phyllodes Tumors of the Breast: A Literature Review
title_full Phyllodes Tumors of the Breast: A Literature Review
title_fullStr Phyllodes Tumors of the Breast: A Literature Review
title_full_unstemmed Phyllodes Tumors of the Breast: A Literature Review
title_short Phyllodes Tumors of the Breast: A Literature Review
title_sort phyllodes tumors of the breast: a literature review
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478785/
https://www.ncbi.nlm.nih.gov/pubmed/32923300
http://dx.doi.org/10.7759/cureus.10288
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