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IL-10 from dendritic cells but not from T regulatory cells protects against cisplatin-induced nephrotoxicity

Interleukin-10 (IL-10), a cytokine with anti-inflammatory effects, is produced by renal parenchymal cells and bone marrow derived cells. Both endogenous and exogenous IL-10 are protective in cisplatin-induced acute kidney injury. However, the source of endogenous IL-10 in cisplatin-induced nephrotox...

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Detalles Bibliográficos
Autores principales: Wang, Wei Wei, Wang, Yamei, Li, Kang, Tadagavadi, Raghu, Friedrichs, William E., Budatha, Madhusudhan, Reeves, W. Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478814/
https://www.ncbi.nlm.nih.gov/pubmed/32898157
http://dx.doi.org/10.1371/journal.pone.0238816