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Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
Sphingolipids are abundant and essential molecules in eukaryotes that have crucial functions as signaling molecules and as membrane components. Sphingolipid biosynthesis starts in the endoplasmic reticulum with the condensation of serine and palmitoyl-CoA. Sphingolipid biosynthesis is highly regulat...
Autores principales: | Esch, Bianca M., Limar, Sergej, Bogdanowski, André, Gournas, Christos, More, Tushar, Sundag, Celine, Walter, Stefan, Heinisch, Jürgen J., Ejsing, Christer S., André, Bruno, Fröhlich, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478846/ https://www.ncbi.nlm.nih.gov/pubmed/32845888 http://dx.doi.org/10.1371/journal.pgen.1008745 |
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