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How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential
Study reveals that, at low acetylcholine concentrations, calcium enhances channel opening by binding to a novel motif near the ligand binding site.
Autor principal: | |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478870/ https://www.ncbi.nlm.nih.gov/pubmed/32820805 http://dx.doi.org/10.1085/jgp.202012740 |
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author | Short, Ben |
author_facet | Short, Ben |
author_sort | Short, Ben |
collection | PubMed |
description | Study reveals that, at low acetylcholine concentrations, calcium enhances channel opening by binding to a novel motif near the ligand binding site. |
format | Online Article Text |
id | pubmed-7478870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74788702021-03-07 How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential Short, Ben J Gen Physiol Research News Study reveals that, at low acetylcholine concentrations, calcium enhances channel opening by binding to a novel motif near the ligand binding site. Rockefeller University Press 2020-08-20 /pmc/articles/PMC7478870/ /pubmed/32820805 http://dx.doi.org/10.1085/jgp.202012740 Text en © 2020 Rockefeller University Press http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Research News Short, Ben How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title | How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title_full | How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title_fullStr | How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title_full_unstemmed | How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title_short | How calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
title_sort | how calcium helps α7 nicotinic acetylcholine receptors fulfill their potential |
topic | Research News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478870/ https://www.ncbi.nlm.nih.gov/pubmed/32820805 http://dx.doi.org/10.1085/jgp.202012740 |
work_keys_str_mv | AT shortben howcalciumhelpsa7nicotinicacetylcholinereceptorsfulfilltheirpotential |