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ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

A human cell contains hundreds to thousands of mitochondrial DNA (mtDNA) packaged into nucleoids. Currently, the segregation and allocation of nucleoids are thought to be passively determined by mitochondrial fusion and division. Here we provide evidence, using live-cell super-resolution imaging, th...

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Detalles Bibliográficos
Autores principales: Qin, Jinshan, Guo, Yuting, Xue, Boxin, Shi, Peng, Chen, Yang, Su, Qian Peter, Hao, Huiwen, Zhao, Shujuan, Wu, Congying, Yu, Li, Li, Dong, Sun, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478960/
https://www.ncbi.nlm.nih.gov/pubmed/32901010
http://dx.doi.org/10.1038/s41467-020-18202-4