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FastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples
Dissecting tumor heterogeneity is a key to understanding the complex mechanisms underlying drug resistance in cancers. The rich literature of pioneering studies on tumor heterogeneity analysis spurred a recent community-wide benchmark study that compares diverse modeling algorithms. Here we present...
Autores principales: | Xiao, Yao, Wang, Xueqing, Zhang, Hongjiu, Ulintz, Peter J., Li, Hongyang, Guan, Yuanfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478963/ https://www.ncbi.nlm.nih.gov/pubmed/32901013 http://dx.doi.org/10.1038/s41467-020-18169-2 |
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