Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Innate lymphoid cells (ILCs) and CD4(+) T cells produce IL-22, which is critical for intestinal immunity. The microbiota is central to IL-22 production in the intestines; however, the factors that regulate IL-22 production by CD4(+) T cells and ILCs are not clear. Here, we show that microbiota-deriv...

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Detalles Bibliográficos
Autores principales: Yang, Wenjing, Yu, Tianming, Huang, Xiangsheng, Bilotta, Anthony J., Xu, Leiqi, Lu, Yao, Sun, Jiaren, Pan, Fan, Zhou, Jia, Zhang, Wenbo, Yao, Suxia, Maynard, Craig L., Singh, Nagendra, Dann, Sara M., Liu, Zhanju, Cong, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478978/
https://www.ncbi.nlm.nih.gov/pubmed/32901017
http://dx.doi.org/10.1038/s41467-020-18262-6

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