Synthetic Naphthofuranquinone Derivatives Are Effective in Eliminating Drug-Resistant Candida albicans in Hyphal, Biofilm, and Intracellular Forms: An Application for Skin-Infection Treatment

Candida albicans is the most common cause of fungal infection. The emergence of drug resistance leads to the need for novel antifungal agents. We aimed to design naphthofuranquinone analogs to treat drug-resistant C. albicans for topical application on cutaneous candidiasis. The time-killing respons...

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Detalles Bibliográficos
Autores principales: Fang, Jia-You, Tang, Kai-Wei, Yang, Sien-Hung, Alalaiwe, Ahmed, Yang, Yu-Ching, Tseng, Chih-Hua, Yang, Shih-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479094/
https://www.ncbi.nlm.nih.gov/pubmed/32983038
http://dx.doi.org/10.3389/fmicb.2020.02053

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