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High MHC-II expression in Epstein–Barr virus-associated gastric cancers suggests that tumor cells serve an important role in antigen presentation
EBV-associated gastric adenocarcinomas (EBVaGCs) often exhibit better clinical outcomes than EBV negative gastric cancers (GCs), which could be related to their consistent expression of foreign viral antigens. Antigen-presenting cells (APCs) present peptide antigens in the context of the class-II ma...
Autores principales: | Ghasemi, Farhad, Tessier, Tanner M., Gameiro, Steven F., Maciver, Allison H., Cecchini, Matthew J., Mymryk, Joe S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479113/ https://www.ncbi.nlm.nih.gov/pubmed/32901107 http://dx.doi.org/10.1038/s41598-020-71775-4 |
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