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Exhausted CD8(+) T cells exhibit low and strongly inhibited TCR signaling during chronic LCMV infection
Chronic viral infections are often associated with impaired CD8(+) T cell function, referred to as exhaustion. Although the molecular and cellular circuits involved in CD8(+) T cell exhaustion are well defined, with sustained presence of antigen being one important parameter, how much T cell recepto...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479152/ https://www.ncbi.nlm.nih.gov/pubmed/32901001 http://dx.doi.org/10.1038/s41467-020-18256-4 |