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Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis – The promise of DNA methylation and molecular biomarkers

Cholangiocarcinoma (CCA) is a highly fatal malignancy of the bile ducts that arises in up to 20% of patients with primary sclerosing cholangitis (PSC). Current detection methods for CCA display suboptimal sensitivity and/or specificity, and there is no evidence-based screening strategy for CCA in pa...

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Detalles Bibliográficos
Autores principales: Vedeld, Hege Marie, Folseraas, Trine, Lind, Guro Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479288/
https://www.ncbi.nlm.nih.gov/pubmed/32939446
http://dx.doi.org/10.1016/j.jhepr.2020.100143