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Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?

BACKGROUND: The observations of some recent epidemiological studies offer hope for a reduced impact of COVID-19 for countries which practice universal BCG vaccination policy. MAIN BODY: This report provides a correlation between the case fatality rates of COVID-19 and the percentage of BCG vaccinati...

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Autores principales: Mohamed Hussein, Aliae A. R., Salem, Marwa Rashad, Salman, Samar, Abdulrahim, A F, Al Massry, Nasrallah A., Saad, Mahmoud, Dahman, Nesrine Ben Hadj, Negida, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479298/
http://dx.doi.org/10.1186/s43168-020-00022-1
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author Mohamed Hussein, Aliae A. R.
Salem, Marwa Rashad
Salman, Samar
Abdulrahim, A F
Al Massry, Nasrallah A.
Saad, Mahmoud
Dahman, Nesrine Ben Hadj
Negida, Ahmed
author_facet Mohamed Hussein, Aliae A. R.
Salem, Marwa Rashad
Salman, Samar
Abdulrahim, A F
Al Massry, Nasrallah A.
Saad, Mahmoud
Dahman, Nesrine Ben Hadj
Negida, Ahmed
author_sort Mohamed Hussein, Aliae A. R.
collection PubMed
description BACKGROUND: The observations of some recent epidemiological studies offer hope for a reduced impact of COVID-19 for countries which practice universal BCG vaccination policy. MAIN BODY: This report provides a correlation between the case fatality rates of COVID-19 and the percentage of BCG vaccination coverage in 183 most affected countries. The main objective of this observational ecologic report is to evaluate possible effects of the previous BCG vaccination in different populations and the epidemic outcomes specially the rates of severe/critical cases and case fatalities. The analysis is preliminary since it is based on constantly rolling data while the COVID-19 pandemic is still unfolding. CONCLUSION: Our findings seem to support the fact that an older BCG vaccine may have a protective role in avoiding severe/critical SARS-CoV2 pneumonia and relatively decrease its fatalities.
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spelling pubmed-74792982020-09-09 Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective? Mohamed Hussein, Aliae A. R. Salem, Marwa Rashad Salman, Samar Abdulrahim, A F Al Massry, Nasrallah A. Saad, Mahmoud Dahman, Nesrine Ben Hadj Negida, Ahmed Egypt J Bronchol Commentaries BACKGROUND: The observations of some recent epidemiological studies offer hope for a reduced impact of COVID-19 for countries which practice universal BCG vaccination policy. MAIN BODY: This report provides a correlation between the case fatality rates of COVID-19 and the percentage of BCG vaccination coverage in 183 most affected countries. The main objective of this observational ecologic report is to evaluate possible effects of the previous BCG vaccination in different populations and the epidemic outcomes specially the rates of severe/critical cases and case fatalities. The analysis is preliminary since it is based on constantly rolling data while the COVID-19 pandemic is still unfolding. CONCLUSION: Our findings seem to support the fact that an older BCG vaccine may have a protective role in avoiding severe/critical SARS-CoV2 pneumonia and relatively decrease its fatalities. Springer Berlin Heidelberg 2020-09-09 2020 /pmc/articles/PMC7479298/ http://dx.doi.org/10.1186/s43168-020-00022-1 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentaries
Mohamed Hussein, Aliae A. R.
Salem, Marwa Rashad
Salman, Samar
Abdulrahim, A F
Al Massry, Nasrallah A.
Saad, Mahmoud
Dahman, Nesrine Ben Hadj
Negida, Ahmed
Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title_full Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title_fullStr Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title_full_unstemmed Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title_short Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?
title_sort correlation between covid-19 case fatality rate and percentage of bcg vaccination: is it true the vaccine is protective?
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479298/
http://dx.doi.org/10.1186/s43168-020-00022-1
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