Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation

A major challenge to the development of therapies for human retinal degenerative diseases is the lack of an ideal preclinical model because of the physiological differences between humans and most model animals. Despite the successful generation of a primate model through germline knockout of a dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Qiang, Lv, Ji-Neng, Wu, Kun-Chao, Zhang, Chang-Jun, Liu, Qin, Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479327/
https://www.ncbi.nlm.nih.gov/pubmed/32953936
http://dx.doi.org/10.1016/j.omtm.2020.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479327/
https://www.ncbi.nlm.nih.gov/pubmed/32953936
http://dx.doi.org/10.1016/j.omtm.2020.08.007

Ejemplares similares