Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism

AIMS/HYPOTHESIS: This study aimed to examine if beta-aminoisobutyric acid (BAIBA) is (i) secreted by skeletal muscle in humans during exercise, (ii) associated with insulin secretory function in vivo, and (iii) directly linked with acute glucose-mediated insulin release by pancreatic beta cells in v...

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Detalles Bibliográficos
Autores principales: Barlow, Jonathan P., Karstoft, Kristian, Vigelsø, Andreas, Gram, Martin, Helge, Jørn W., Dela, Flemming, Pappan, Kirk, O’Neil, Donna, Dunn, Warwick, Solomon, Thomas P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479356/
https://www.ncbi.nlm.nih.gov/pubmed/32924003
http://dx.doi.org/10.1016/j.metop.2020.100053

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