Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test

The diagnostic performance of ImmunoFLOW, a rapid test for detecting herpes simplex virus type-2 (HSV-2) infections, was investigated in 248 antenatal women. Approximately one hundred and seventy-seven (71%) of the enrolled women were infected with HSV-2. Sero-positivity was associated with older ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Govender, Shanthie, Mbambo, Lungile, Nyirenda, Makandwe, Sebitloane, Motshedisi, Abbai, Nathlee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479370/
https://www.ncbi.nlm.nih.gov/pubmed/32934909
http://dx.doi.org/10.4102/ajlm.v9i1.854
_version_ 1783580257217937408
author Govender, Shanthie
Mbambo, Lungile
Nyirenda, Makandwe
Sebitloane, Motshedisi
Abbai, Nathlee
author_facet Govender, Shanthie
Mbambo, Lungile
Nyirenda, Makandwe
Sebitloane, Motshedisi
Abbai, Nathlee
author_sort Govender, Shanthie
collection PubMed
description The diagnostic performance of ImmunoFLOW, a rapid test for detecting herpes simplex virus type-2 (HSV-2) infections, was investigated in 248 antenatal women. Approximately one hundred and seventy-seven (71%) of the enrolled women were infected with HSV-2. Sero-positivity was associated with older age ([≥ 30 years] 104/177, 58%), having a secondary level of education but not tertiary level of education (125/177, 70.6%), and being unmarried (150/177, 84.7%). The sensitivity of the ImmunoFLOW test in relation to the HerpeSelect HSV-2 enzyme-linked immunosorbent assay was 89.7% and specificity was 96.2%. The ImmunoFLOW therefore can serve as a valuable test in screening for HSV-2 infections in pregnant women.
format Online
Article
Text
id pubmed-7479370
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher AOSIS
record_format MEDLINE/PubMed
spelling pubmed-74793702020-09-14 Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test Govender, Shanthie Mbambo, Lungile Nyirenda, Makandwe Sebitloane, Motshedisi Abbai, Nathlee Afr J Lab Med Brief Report The diagnostic performance of ImmunoFLOW, a rapid test for detecting herpes simplex virus type-2 (HSV-2) infections, was investigated in 248 antenatal women. Approximately one hundred and seventy-seven (71%) of the enrolled women were infected with HSV-2. Sero-positivity was associated with older age ([≥ 30 years] 104/177, 58%), having a secondary level of education but not tertiary level of education (125/177, 70.6%), and being unmarried (150/177, 84.7%). The sensitivity of the ImmunoFLOW test in relation to the HerpeSelect HSV-2 enzyme-linked immunosorbent assay was 89.7% and specificity was 96.2%. The ImmunoFLOW therefore can serve as a valuable test in screening for HSV-2 infections in pregnant women. AOSIS 2020-08-31 /pmc/articles/PMC7479370/ /pubmed/32934909 http://dx.doi.org/10.4102/ajlm.v9i1.854 Text en © 2020. The Authors https://creativecommons.org/licenses/by/4.0/ Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Brief Report
Govender, Shanthie
Mbambo, Lungile
Nyirenda, Makandwe
Sebitloane, Motshedisi
Abbai, Nathlee
Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title_full Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title_fullStr Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title_full_unstemmed Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title_short Herpes simplex virus-2 infections in pregnant women from South Africa: Evaluation of the ImmunoFLOW rapid test
title_sort herpes simplex virus-2 infections in pregnant women from south africa: evaluation of the immunoflow rapid test
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479370/
https://www.ncbi.nlm.nih.gov/pubmed/32934909
http://dx.doi.org/10.4102/ajlm.v9i1.854
work_keys_str_mv AT govendershanthie herpessimplexvirus2infectionsinpregnantwomenfromsouthafricaevaluationoftheimmunoflowrapidtest
AT mbambolungile herpessimplexvirus2infectionsinpregnantwomenfromsouthafricaevaluationoftheimmunoflowrapidtest
AT nyirendamakandwe herpessimplexvirus2infectionsinpregnantwomenfromsouthafricaevaluationoftheimmunoflowrapidtest
AT sebitloanemotshedisi herpessimplexvirus2infectionsinpregnantwomenfromsouthafricaevaluationoftheimmunoflowrapidtest
AT abbainathlee herpessimplexvirus2infectionsinpregnantwomenfromsouthafricaevaluationoftheimmunoflowrapidtest

Ejemplares similares