CERE-120 Prevents Irradiation-Induced Hypofunction and Restores Immune Homeostasis in Porcine Salivary Glands

Salivary gland hypofunction causes significant morbidity and loss of quality of life for head and neck cancer patients treated with radiotherapy. Preventing hypofunction is an unmet therapeutic need. We used an adeno-associated virus serotype 2 (AAV2) vector expressing the human neurotrophic factor...

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Detalles Bibliográficos
Autores principales: Lombaert, Isabelle M.A., Patel, Vaishali N., Jones, Christina E., Villier, Derrick C., Canada, Ashley E., Moore, Matthew R., Berenstein, Elsa, Zheng, Changyu, Goldsmith, Corinne M., Chorini, John A., Martin, Daniel, Zourelias, Lee, Trombetta, Mark G., Edwards, Paul C., Meyer, Kathleen, Ando, Dale, Passineau, Michael J., Hoffman, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479444/
https://www.ncbi.nlm.nih.gov/pubmed/32953934
http://dx.doi.org/10.1016/j.omtm.2020.07.016

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