Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

Assessment of internal tandem duplications in FLT3 (FLT3-ITDs) and their allelic ratio (AR) is recommended by clinical guidelines for diagnostic workup of acute myeloid leukemia and traditionally performed through capillary electrophoresis (CE). Although significant progress has been made integratin...

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Detalles Bibliográficos
Autores principales: Tsai, Harrison K., Brackett, Diane G., Szeto, David, Frazier, Ryan, MacLeay, Allison, Davineni, Phani, Manning, Danielle K., Garcia, Elizabeth, Lindeman, Neal I., Le, Long P., Lennerz, Jochen K., Gibson, Christopher J., Lindsley, R. Coleman, Kim, Annette S., Nardi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479488/
https://www.ncbi.nlm.nih.gov/pubmed/32603763
http://dx.doi.org/10.1016/j.jmoldx.2020.06.006

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