Cargando…

Cucurbitacin E Induces Autophagy-Involved Apoptosis in Intestinal Epithelial Cells

Apoptosis plays a crucial role in maintaining the structural and functional integrity of the intestinal epithelial barrier. Autophagy mediates injury to and repair of the intestinal epithelial barrier through multiple pathways in pathophysiological conditions. Our earlier study has found that cucurb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Huapei, Sui, Hehuan, Zhang, Qiong, Wang, Pei, Wang, Fengjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479753/ https://www.ncbi.nlm.nih.gov/pubmed/32982778 http://dx.doi.org/10.3389/fphys.2020.01020

Ejemplares similares

Cucurbitacin E Inhibits Proliferation and Migration of Intestinal Epithelial Cells via Activating Cofilin
por: Song, Huapei, et al.
Publicado: (2018)

Activation of Cofilin Increases Intestinal Permeability via Depolymerization of F-Actin During Hypoxia in vitro
por: Song, Huapei, et al.
Publicado: (2019)

Severe Burn-Induced Intestinal Epithelial Barrier Dysfunction Is Associated With Endoplasmic Reticulum Stress and Autophagy in Mice
por: Huang, Yalan, et al.
Publicado: (2018)

Antibiotics induced intestinal tight junction barrier dysfunction is associated with microbiota dysbiosis, activated NLRP3 inflammasome and autophagy
por: Feng, Yanhai, et al.
Publicado: (2019)

Role of Endoplasmic Reticulum Stress-Autophagy Axis in Severe Burn-Induced Intestinal Tight Junction Barrier Dysfunction in Mice
por: Huang, Yalan, et al.
Publicado: (2019)

Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression
por: Liu, Wen-Bei, et al.
Publicado: (2022)

Cucurbitacin E and I target the JAK/STAT pathway and induce apoptosis in Sézary cells
por: Brouwer, Isabella J., et al.
Publicado: (2020)

Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity
por: Zha, Qing-Bing, et al.
Publicado: (2015)

Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis
por: Chang, Jui-Chih, et al.
Publicado: (2019)

PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells
por: Niu, Yanan, et al.
Publicado: (2016)

Cucurbitacin E as Inducer of Cell Death and Apoptosis in Human Oral Squamous Cell Carcinoma Cell Line SAS
por: Hung, Chao-Ming, et al.
Publicado: (2013)

Synthesis of cucurbitacin IIa derivatives with apoptosis-inducing capabilities in human cancer cells
por: Yu, Kun, et al.
Publicado: (2020)

SHANK3 Co-ordinately Regulates Autophagy and Apoptosis in Myocardial Infarction
por: Man, Wanrong, et al.
Publicado: (2020)

Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer
por: Kong, Yanjie, et al.
Publicado: (2014)

Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways
por: Huang, Jian-Lan, et al.
Publicado: (2023)

Cucurbitacins: elucidation of their interactions with the cytoskeleton
por: Wang, Xiaojuan, et al.
Publicado: (2017)

Cucurbitacin B Exerts Antiaging Effects in Yeast by Regulating Autophagy and Oxidative Stress
por: Lin, Yanfei, et al.
Publicado: (2019)

Inducement of apoptosis by cucurbitacin E, a tetracyclic triterpenes, through death receptor 5 in human cervical cancer cell lines
por: Cheng, Ya-Min, et al.
Publicado: (2017)

Novel Role of ER Stress and Autophagy in Microcystin-LR Induced Apoptosis in Chinese Hamster Ovary Cells
por: Zhang, Shenshen, et al.
Publicado: (2016)

Extracellular Vesicles From High Glucose-Treated Podocytes Induce Apoptosis of Proximal Tubular Epithelial Cells
por: Huang, Ying, et al.
Publicado: (2020)

Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity
por: Zhao, Yuxiao, et al.
Publicado: (2020)

Spermidine alleviating oxidative stress and apoptosis by inducing autophagy of granulosa cells in Sichuan white geese
por: Jiang, Dongmei, et al.
Publicado: (2023)

Pharmacokinetics and Biological Activity of Cucurbitacins
por: Delgado-Tiburcio, Eugenia Elisa, et al.
Publicado: (2022)

Autophagy is Involved in Cardiac Remodeling in Response to Environmental Temperature Change
por: Ruperez, C., et al.
Publicado: (2022)

The involvement of the noradrenergic system in the antinociceptive effect of cucurbitacin D on mice with paclitaxel-induced neuropathic pain
por: Park, Keun-Tae, et al.
Publicado: (2023)

Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E
por: Ren, Lingli, et al.
Publicado: (2022)

Photoperiod Affects Harderian Gland Morphology and Secretion in Female Cricetulus barabensis: Autophagy, Apoptosis, and Mitochondria
por: Wang, Zhe, et al.
Publicado: (2020)

Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells
por: Qu, Yingchun, et al.
Publicado: (2017)

Beneficial Effects of Polysaccharides on the Epithelial Barrier Function in Intestinal Mucositis
por: Sauruk da Silva, Karien, et al.
Publicado: (2021)

Capsaicin Attenuates Lipopolysaccharide-Induced Inflammation and Barrier Dysfunction in Intestinal Porcine Epithelial Cell Line-J2
por: Zhao, Xiaoya, et al.
Publicado: (2021)

Close Homolog of L1 Deficiency Exacerbated Intestinal Epithelial Barrier Function in Mouse Model of Dextran Sulfate Sodium-Induced Colitis
por: Han, Ying, et al.
Publicado: (2020)

Unraveling the Proteomic Landscape of Intestinal Epithelial Cell-Derived Exosomes in Mice
por: Ding, Zhenyu, et al.
Publicado: (2022)

Autophagy Is Involved in Stellate Ganglion Block Reversing Posthemorrhagic Shock Mesenteric Lymph-Mediated Vascular Hyporeactivity
por: Wang, Chen, et al.
Publicado: (2021)

miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation
por: Song, Nana, et al.
Publicado: (2018)

Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells
por: ZHANG, MENG, et al.
Publicado: (2014)

E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy
por: Lescouzères, Léa, et al.
Publicado: (2020)

Indicaxanthin Induces Autophagy in Intestinal Epithelial Cancer Cells by Epigenetic Mechanisms Involving DNA Methylation
por: Ragusa, Maria Antonietta, et al.
Publicado: (2023)

GADD45B Promotes Glucose-Induced Renal Tubular Epithelial-Mesenchymal Transition and Apoptosis via the p38 MAPK and JNK Signaling Pathways
por: Xue, Mei, et al.
Publicado: (2020)

Amelioration of IFN-γ and TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Berberine via Suppression of MLCK-MLC Phosphorylation Signaling Pathway
por: Cao, Min, et al.
Publicado: (2013)

Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons
por: Arel-Dubeau, Anne-Marie, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dd9m8ur2j1sphdeo55qh7ua1qo