Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Blood–spinal cord barrier (BSCB) disruption is thought to contribute to motoneuron (MN) loss in amyotrophic lateral sclerosis (ALS). It is currently unclear whether impairment of the BSCB is the cause or consequence of MN dysfunction and whether its restoration may be directly beneficial. We reveale...

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Detalles Bibliográficos
Autores principales: Ouali Alami, Najwa, Tang, Linyun, Wiesner, Diana, Commisso, Barbara, Bayer, David, Weishaupt, Jochen, Dupuis, Luc, Wong, Phillip, Baumann, Bernd, Wirth, Thomas, Boeckers, Tobias M, Yilmazer-Hanke, Deniz, Ludolph, Albert, Roselli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479971/
https://www.ncbi.nlm.nih.gov/pubmed/32900826
http://dx.doi.org/10.26508/lsa.201900571

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