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Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function

Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility...

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Detalles Bibliográficos
Autores principales: Moura-Neto, José A., Misael, Ana Maria, da Silva, Dirceu Reis, D’Avila, Ronaldo, Andreoli, Maria Claudia Cruz, Kraychete, Angiolina, Bastos, Kleyton, do Nascimento, Marcelo Mazza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479979/
https://www.ncbi.nlm.nih.gov/pubmed/32877501
http://dx.doi.org/10.1590/2175-8239-JBN-2020-S113
Descripción
Sumario:Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility of the attending physician and should be individualized and shared, whenever possible. This position statement recommends dosage adjustment for these drugs in the context of renal impairment.