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Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function

Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility...

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Autores principales: Moura-Neto, José A., Misael, Ana Maria, da Silva, Dirceu Reis, D’Avila, Ronaldo, Andreoli, Maria Claudia Cruz, Kraychete, Angiolina, Bastos, Kleyton, do Nascimento, Marcelo Mazza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479979/
https://www.ncbi.nlm.nih.gov/pubmed/32877501
http://dx.doi.org/10.1590/2175-8239-JBN-2020-S113
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author Moura-Neto, José A.
Misael, Ana Maria
da Silva, Dirceu Reis
D’Avila, Ronaldo
Andreoli, Maria Claudia Cruz
Kraychete, Angiolina
Bastos, Kleyton
do Nascimento, Marcelo Mazza
author_facet Moura-Neto, José A.
Misael, Ana Maria
da Silva, Dirceu Reis
D’Avila, Ronaldo
Andreoli, Maria Claudia Cruz
Kraychete, Angiolina
Bastos, Kleyton
do Nascimento, Marcelo Mazza
author_sort Moura-Neto, José A.
collection PubMed
description Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility of the attending physician and should be individualized and shared, whenever possible. This position statement recommends dosage adjustment for these drugs in the context of renal impairment.
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spelling pubmed-74799792020-09-17 Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function Moura-Neto, José A. Misael, Ana Maria da Silva, Dirceu Reis D’Avila, Ronaldo Andreoli, Maria Claudia Cruz Kraychete, Angiolina Bastos, Kleyton do Nascimento, Marcelo Mazza J Bras Nefrol Recommendations Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility of the attending physician and should be individualized and shared, whenever possible. This position statement recommends dosage adjustment for these drugs in the context of renal impairment. Sociedade Brasileira de Nefrologia 2020-08-26 2020 /pmc/articles/PMC7479979/ /pubmed/32877501 http://dx.doi.org/10.1590/2175-8239-JBN-2020-S113 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Recommendations
Moura-Neto, José A.
Misael, Ana Maria
da Silva, Dirceu Reis
D’Avila, Ronaldo
Andreoli, Maria Claudia Cruz
Kraychete, Angiolina
Bastos, Kleyton
do Nascimento, Marcelo Mazza
Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title_full Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title_fullStr Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title_full_unstemmed Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title_short Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
title_sort position statement from the brazilian society of nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function
topic Recommendations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479979/
https://www.ncbi.nlm.nih.gov/pubmed/32877501
http://dx.doi.org/10.1590/2175-8239-JBN-2020-S113
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