Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration(1,2). This adaptability is lost in cultured adult endothelial cells, which do not vascularize tissues in an organotypic manner. Here, we show that transient reactivation of the embryonic-restricted...

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Detalles Bibliográficos
Autores principales: Palikuqi, Brisa, Nguyen, Duc-Huy T., Li, Ge, Schreiner, Ryan, Pellegata, Alessandro F., Liu, Ying, Redmond, David, Geng, Fuqiang, Lin, Yang, Gómez-Salinero, Jesus M., Yokoyama, Masataka, Zumbo, Paul, Zhang, Tuo, Kunar, Balvir, Witherspoon, Mavee, Han, Teng, Tedeschi, Alfonso M., Scottoni, Federico, Lipkin, Steven M., Dow, Lukas, Elemento, Olivier, Xiang, Jenny Z., Shido, Koji, Spence, Jason R., Zhou, Qiao J., Schwartz, Robert E., De Coppi, Paolo, Rabbany, Sina Y., Rafii, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480005/
https://www.ncbi.nlm.nih.gov/pubmed/32908310
http://dx.doi.org/10.1038/s41586-020-2712-z

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