Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication

Reprogrammed pluripotent stem cells (PSCs) are valuable for research and potentially for cell replacement therapy. However, only a fraction of reprogrammed PSCs are developmentally competent. Genomic stability and accurate DNA synthesis are fundamental for cell development and critical for safety. W...

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Detalles Bibliográficos
Autores principales: Paniza, Theodore, Deshpande, Madhura, Wang, Ning, O’Neil, Ryan, Zuccaro, Michael V., Smith, Morgan Elizabeth, Madireddy, Advaitha, James, Daylon, Ecker, Joseph, Rosenwaks, Zev, Egli, Dieter, Gerhardt, Jeannine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480103/
https://www.ncbi.nlm.nih.gov/pubmed/32673399
http://dx.doi.org/10.1083/jcb.201909163

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