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Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks

Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of soma...

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Detalles Bibliográficos
Autores principales: Mouery, Brandon L., Mei, Liu, Cook, Jeanette Gowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480109/
https://www.ncbi.nlm.nih.gov/pubmed/32858750
http://dx.doi.org/10.1083/jcb.202008014
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author Mouery, Brandon L.
Mei, Liu
Cook, Jeanette Gowen
author_facet Mouery, Brandon L.
Mei, Liu
Cook, Jeanette Gowen
author_sort Mouery, Brandon L.
collection PubMed
description Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of somatic DNA replication origin utilization and suffer more frequent DNA damage.
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spelling pubmed-74801092021-03-07 Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks Mouery, Brandon L. Mei, Liu Cook, Jeanette Gowen J Cell Biol Spotlight Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of somatic DNA replication origin utilization and suffer more frequent DNA damage. Rockefeller University Press 2020-08-27 /pmc/articles/PMC7480109/ /pubmed/32858750 http://dx.doi.org/10.1083/jcb.202008014 Text en © 2020 Mouery et al. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Mouery, Brandon L.
Mei, Liu
Cook, Jeanette Gowen
Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title_full Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title_fullStr Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title_full_unstemmed Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title_short Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
title_sort programming pluripotent stem cells: can't teach an old cell new dna replication tricks
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480109/
https://www.ncbi.nlm.nih.gov/pubmed/32858750
http://dx.doi.org/10.1083/jcb.202008014
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