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Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks
Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of soma...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480109/ https://www.ncbi.nlm.nih.gov/pubmed/32858750 http://dx.doi.org/10.1083/jcb.202008014 |
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author | Mouery, Brandon L. Mei, Liu Cook, Jeanette Gowen |
author_facet | Mouery, Brandon L. Mei, Liu Cook, Jeanette Gowen |
author_sort | Mouery, Brandon L. |
collection | PubMed |
description | Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of somatic DNA replication origin utilization and suffer more frequent DNA damage. |
format | Online Article Text |
id | pubmed-7480109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74801092021-03-07 Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks Mouery, Brandon L. Mei, Liu Cook, Jeanette Gowen J Cell Biol Spotlight Pluripotent stem cells differentiate with varying efficiencies depending on the method of reprogramming that created them. In this issue, Paniza et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201909163) demonstrate that cells with lower differentiation potential retain some features of somatic DNA replication origin utilization and suffer more frequent DNA damage. Rockefeller University Press 2020-08-27 /pmc/articles/PMC7480109/ /pubmed/32858750 http://dx.doi.org/10.1083/jcb.202008014 Text en © 2020 Mouery et al. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Spotlight Mouery, Brandon L. Mei, Liu Cook, Jeanette Gowen Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title | Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title_full | Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title_fullStr | Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title_full_unstemmed | Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title_short | Programming pluripotent stem cells: Can't teach an old cell new DNA replication tricks |
title_sort | programming pluripotent stem cells: can't teach an old cell new dna replication tricks |
topic | Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480109/ https://www.ncbi.nlm.nih.gov/pubmed/32858750 http://dx.doi.org/10.1083/jcb.202008014 |
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