Cargando…
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion
Fast amoeboid migration is critical for developmental processes and can be hijacked by cancer cells to enhance metastatic dissemination. This migratory behavior is tightly controlled by high levels of actomyosin contractility, but how it is coupled to other cytoskeletal components is poorly understo...
Autores principales: | Farrugia, Aaron J., Rodríguez, Javier, Orgaz, Jose L., Lucas, María, Sanz-Moreno, Victoria, Calvo, Fernando |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480113/ https://www.ncbi.nlm.nih.gov/pubmed/32798219 http://dx.doi.org/10.1083/jcb.201912159 |
Ejemplares similares
-
The Borg family of Cdc42 effector proteins Cdc42EP1–5
por: Farrugia, Aaron J., et al.
Publicado: (2016) -
Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
por: Farrugia, Aaron J., et al.
Publicado: (2016) -
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts
por: Calvo, Fernando, et al.
Publicado: (2015) -
Actomyosin contractility and collective migration: may the force be with you
por: Pandya, Pahini, et al.
Publicado: (2017) -
CDC42 Negatively Regulates Testis-Specific SEPT12 Polymerization
por: Huang, Chia-Yen, et al.
Publicado: (2018)