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Nuclear role for human Argonaute-1 as an estrogen-dependent transcription coactivator
In mammals, argonaute (AGO) proteins have been characterized for their roles in small RNA–mediated posttranscriptional and also in transcriptional gene silencing. Here, we report a different role for AGO1 in estradiol-triggered transcriptional activation in human cells. We show that in MCF-7 mammary...
Autores principales: | Gómez Acuña, Luciana I., Nazer, Ezequiel, Rodríguez-Seguí, Santiago A., Pozzi, Berta, Buggiano, Valeria, Marasco, Luciano E., Agirre, Eneritz, He, Cody, Alló, Mariano, Kornblihtt, Alberto R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480116/ https://www.ncbi.nlm.nih.gov/pubmed/32673398 http://dx.doi.org/10.1083/jcb.201908097 |
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