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The function of GORASPs in Golgi apparatus organization in vivo

In vitro experiments have shown that GRASP65 (GORASP1) and GRASP55 (GORASP2) proteins function in stacking Golgi cisternae. However, in vivo depletion of GORASPs in metazoans has given equivocal results. We have generated a mouse lacking both GORASPs and find that Golgi cisternae remained stacked. H...

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Detalles Bibliográficos
Autores principales: Grond, Rianne, Veenendaal, Tineke, Duran, Juan M., Raote, Ishier, van Es, Johan H., Corstjens, Sebastiaan, Delfgou, Laura, El Haddouti, Benaissa, Malhotra, Vivek, Rabouille, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480117/
https://www.ncbi.nlm.nih.gov/pubmed/32573693
http://dx.doi.org/10.1083/jcb.202004191