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Non-cytotoxic doses of shikonin inhibit lipopolysaccharide-induced TNF-α expression via activation of the AMP-activated protein kinase signaling pathway

Shikonin has been reported to exhibit a wide variety of medical functions. However, the strong non-selective cytotoxicity of shikonin can restrict its clinical application. The aim of the present study was to investigate the effects of shikonin at non-cytotoxic doses on the pro-inflammation function...

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Detalles Bibliográficos
Autores principales:	Zhang, Fang, Pan, Tao, Wu, Xiaohui, Gao, Xingchun, Li, Zhikui, Ren, Xinling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480124/ https://www.ncbi.nlm.nih.gov/pubmed/32952636 http://dx.doi.org/10.3892/etm.2020.9173

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