Cargando…

Up-Regulation of RIP3 Alleviates Prostate Cancer Progression by Activation of RIP3/MLKL Signaling Pathway and Induction of Necroptosis

BACKGROUND: The receptor-interacting protein kinase 3 (RIP3/RIPK3) was recently found to be a critical regulator of programmed necrosis/necroptosis. However, the biological role and clinical significance of RIP3 in prostate cancer remain obscure. METHODS: Western blotting and QRT-PCR were performed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ke-jie, Wang, Kai-yun, Zhang, Hui-zhi, Meng, Xiang-yu, Chen, Jun-feng, Wang, Ping, Jiang, Jun-hui, Ma, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480187/ https://www.ncbi.nlm.nih.gov/pubmed/32984054 http://dx.doi.org/10.3389/fonc.2020.01720

Ejemplares similares

RIP1/RIP3/MLKL-mediated necroptosis contributes to vinblastine-induced myocardial damage
por: Zhou, Huiling, et al.
Publicado: (2020)

RIP1/RIP3/MLKL Mediates Myocardial Function Through Necroptosis in Experimental Autoimmune Myocarditis
por: Wu, Yujing, et al.
Publicado: (2021)

RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C
por: Guo, Li-Min, et al.
Publicado: (2019)

Necroptosis regulates tumor repopulation after radiotherapy via RIP1/RIP3/MLKL/JNK/IL8 pathway
por: Wang, Yiwei, et al.
Publicado: (2019)

Inhibition of neuronal necroptosis mediated by RIP1/RIP3/MLKL provides neuroprotective effects on kaolin‐induced hydrocephalus in mice
por: Liu, Chang, et al.
Publicado: (2021)

The protective effect of DNA aptamer on osteonecrosis of the femoral head by alleviating TNF-α-mediated necroptosis via RIP1/RIP3/MLKL pathway
por: Fan, Xiaoyu, et al.
Publicado: (2022)

Dapagliflozin Alleviates Renal Fibrosis by Inhibiting RIP1-RIP3-MLKL-Mediated Necroinflammation in Unilateral Ureteral Obstruction
por: Xuan, Mei Ying, et al.
Publicado: (2022)

Macrophage Infiltration Initiates RIP3/MLKL-Dependent Necroptosis in Paclitaxel-Induced Neuropathic Pain
por: Ma, Dongyang, et al.
Publicado: (2022)

RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2019)

The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis
por: Fu, Zeze, et al.
Publicado: (2013)

Life after death: RIP1 and RIP3 move beyond necroptosis
por: Berger, SB, et al.
Publicado: (2016)

TNF-α Triggers RIP1/FADD/Caspase-8-Mediated Apoptosis of Astrocytes and RIP3/MLKL-Mediated Necroptosis of Neurons Induced by Angiostrongylus cantonensis Infection
por: Zhou, Hongli, et al.
Publicado: (2021)

RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review)
por: Liu, Yuping, et al.
Publicado: (2019)

The RIP1–RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats
por: Cui, Hongwang, et al.
Publicado: (2016)

RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif
por: Hu, Hong, et al.
Publicado: (2020)

RIP3 Contributes to Cardiac Hypertrophy by Influencing MLKL-Mediated Calcium Influx
por: Xue, Honghong, et al.
Publicado: (2022)

GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma
por: Liu, Mengyuan, et al.
Publicado: (2022)

Catalytically inactive RIP1 and RIP3 deficiency protect against acute ischemic stroke by inhibiting necroptosis and neuroinflammation
por: Zhang, Yue, et al.
Publicado: (2020)

RIP3 is an upregulator of aerobic metabolism and the enhanced respiration by necrosomal RIP3 feeds back on necrosome to promote necroptosis
por: Qiu, Xingfeng, et al.
Publicado: (2018)

Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway
por: Zhou, Jiabin, et al.
Publicado: (2019)

Cisplatin-Induced Ototoxicity in Rats Is Driven by RIP3-Dependent Necroptosis
por: Choi, Mi-Jin, et al.
Publicado: (2019)

Matrine induces RIP3-dependent necroptosis in cholangiocarcinoma cells
por: Xu, Beibei, et al.
Publicado: (2017)

The brain protection of MLKL inhibitor necrosulfonamide against focal ischemia/reperfusion injury associating with blocking the nucleus and nuclear envelope translocation of MLKL and RIP3K
por: Zhou, Xian-Yong, et al.
Publicado: (2023)

Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis
por: Han, Qinrui, et al.
Publicado: (2018)

HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis
por: Park, Han-Hee, et al.
Publicado: (2018)

RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease
por: Chen, Dongshi, et al.
Publicado: (2021)

Quyu Shengxin Decoction Alleviates DSS-Induced Ulcerative Colitis in Mice by Suppressing RIP1/RIP3/NLRP3 Signalling
por: Wu, Chuang, et al.
Publicado: (2021)

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis
por: Seya, Tsukasa, et al.
Publicado: (2012)

A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis
por: Dowling, John P., et al.
Publicado: (2015)

A Novel Class of RIP1/RIP3 Dual Inhibitors
por: Zhou, Ting, et al.
Publicado: (2020)

Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction
por: Piao, Shang Guo, et al.
Publicado: (2022)

ICP6 Prevents RIP1 Activation to Hinder Necroptosis Signaling
por: Hu, Hong, et al.
Publicado: (2020)

RIP3-mediated microglial necroptosis promotes neuroinflammation and neurodegeneration in the early stages of diabetic retinopathy
por: Huang, Zijing, et al.
Publicado: (2023)

Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury
por: Cruz, Shelly A., et al.
Publicado: (2018)

RIP3-Dependent Accumulation of Mitochondrial Superoxide Anions in TNF-α-Induced Necroptosis
por: Lee, Jiyoung, et al.
Publicado: (2022)

RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
por: Zhang, Yingying, et al.
Publicado: (2017)

Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1
por: Huang, Chuanjiang, et al.
Publicado: (2013)

Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway
por: Liang, Ying-Xia, et al.
Publicado: (2019)

MiR-124 Negatively Regulated PARP1 to Alleviate Renal Ischemia-reperfusion Injury by Inhibiting TNFα/RIP1/RIP3 Pathway
por: Ke, Jing, et al.
Publicado: (2021)

RIP1 and RIP3 mediate hemin-induced cell death in HT22 hippocampal neuronal cells
por: Su, Xingfen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hjuvsmgofvofdeldr5fk5lt7ee