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Synthetic immunomodulation with a CRISPR super-repressor in vivo

Transient modulation of genes involved in immunity, without exerting a permanent change in the DNA code, can be an effective strategy to modulate the course of many inflammatory conditions. CRISPR-Cas9 technology represents a promising platform for achieving this goal. Truncation of guide RNA (gRNA)...

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Detalles Bibliográficos
Autores principales:	Moghadam, Farzaneh, LeGraw, Ryan, Velazquez, Jeremy J, Yeo, Nan Cher, Xu, Chenxi, Park, Jin, Chavez, Alejandro, Ebrahimkhani, Mo R, Kiani, Samira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480217/ https://www.ncbi.nlm.nih.gov/pubmed/32884147 http://dx.doi.org/10.1038/s41556-020-0563-3

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