Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins

The first examples of heterogeneous Fe-catalysed cyclopropanation reactions are presented. Pyrolysis of in situ-generated iron/phenanthroline complexes in the presence of a carbonaceous material leads to specific supported nanosized iron particles, which are effective catalysts for carbene transfer...

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Autores principales: Sarkar, Abhijnan, Formenti, Dario, Ferretti, Francesco, Kreyenschulte, Carsten, Bartling, Stephan, Junge, Kathrin, Beller, Matthias, Ragaini, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480268/
https://www.ncbi.nlm.nih.gov/pubmed/32953016
http://dx.doi.org/10.1039/d0sc01650k
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author Sarkar, Abhijnan
Formenti, Dario
Ferretti, Francesco
Kreyenschulte, Carsten
Bartling, Stephan
Junge, Kathrin
Beller, Matthias
Ragaini, Fabio
author_facet Sarkar, Abhijnan
Formenti, Dario
Ferretti, Francesco
Kreyenschulte, Carsten
Bartling, Stephan
Junge, Kathrin
Beller, Matthias
Ragaini, Fabio
author_sort Sarkar, Abhijnan
collection PubMed
description The first examples of heterogeneous Fe-catalysed cyclopropanation reactions are presented. Pyrolysis of in situ-generated iron/phenanthroline complexes in the presence of a carbonaceous material leads to specific supported nanosized iron particles, which are effective catalysts for carbene transfer reactions. Using olefins as substrates, cyclopropanes are obtained in high yields and moderate diastereoselectivities. The developed protocol is scalable and the activity of the recycled catalyst after deactivation can be effectively restored using an oxidative reactivation protocol under mild conditions.
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spelling pubmed-74802682020-09-18 Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins Sarkar, Abhijnan Formenti, Dario Ferretti, Francesco Kreyenschulte, Carsten Bartling, Stephan Junge, Kathrin Beller, Matthias Ragaini, Fabio Chem Sci Chemistry The first examples of heterogeneous Fe-catalysed cyclopropanation reactions are presented. Pyrolysis of in situ-generated iron/phenanthroline complexes in the presence of a carbonaceous material leads to specific supported nanosized iron particles, which are effective catalysts for carbene transfer reactions. Using olefins as substrates, cyclopropanes are obtained in high yields and moderate diastereoselectivities. The developed protocol is scalable and the activity of the recycled catalyst after deactivation can be effectively restored using an oxidative reactivation protocol under mild conditions. Royal Society of Chemistry 2020-06-08 /pmc/articles/PMC7480268/ /pubmed/32953016 http://dx.doi.org/10.1039/d0sc01650k Text en This journal is © The Royal Society of Chemistry 2020 https://creativecommons.org/licenses/by/3.0/This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
spellingShingle Chemistry
Sarkar, Abhijnan
Formenti, Dario
Ferretti, Francesco
Kreyenschulte, Carsten
Bartling, Stephan
Junge, Kathrin
Beller, Matthias
Ragaini, Fabio
Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title_full Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title_fullStr Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title_full_unstemmed Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title_short Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins
title_sort iron/n-doped graphene nano-structured catalysts for general cyclopropanation of olefins
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480268/
https://www.ncbi.nlm.nih.gov/pubmed/32953016
http://dx.doi.org/10.1039/d0sc01650k
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