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Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?

BACKGROUND AND AIMS: Dextrose is commonly added to the intraoperative maintenance fluids of pediatric patients. The primary objective was to evaluate the effect of addition of 1% dextrose to Ringer's lactate (RL) on blood glucose levels in infants undergoing facial cleft surgeries. MATERIAL AND...

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Autores principales: Rajan, Sunil, Barua, Kaushik, Tosh, Pulak, Kumar, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480286/
https://www.ncbi.nlm.nih.gov/pubmed/33013028
http://dx.doi.org/10.4103/joacp.JOACP_318_18
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author Rajan, Sunil
Barua, Kaushik
Tosh, Pulak
Kumar, Lakshmi
author_facet Rajan, Sunil
Barua, Kaushik
Tosh, Pulak
Kumar, Lakshmi
author_sort Rajan, Sunil
collection PubMed
description BACKGROUND AND AIMS: Dextrose is commonly added to the intraoperative maintenance fluids of pediatric patients. The primary objective was to evaluate the effect of addition of 1% dextrose to Ringer's lactate (RL) on blood glucose levels in infants undergoing facial cleft surgeries. MATERIAL AND METHODS: This prospective, randomized, single blinded study was conducted in forty infants undergoing either cheiloplasty or palatoplasty. Random blood sugar (RBS) was assessed using a glucometer after induction of anaesthesia, and at 1 and 2 hours later. Group R received RL and Group D received RL with 1% dextrose as intraoperative maintenance fluid. Hypoglycemia was defined as RBS <70 mg/dL and hyperglycemia as RBS >150 mg/dL. RESULTS: Baseline RBS levels and those at 60 min and 120 min post-induction were comparable in both groups. The increase in blood sugar levels from baseline to 60 min and to 120 min in each group was significant. Incidence of hyperglycemia was comparable in both groups. There were no episodes of hypoglycemia, intraoperatively. CONCLUSION: Use of Ringer lactate alone or with addition of 1% dextrose resulted in comparable intraoperative blood sugar levels when used as maintenance fluid in infants undergoing facial cleft surgeries.
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spelling pubmed-74802862020-10-02 Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries? Rajan, Sunil Barua, Kaushik Tosh, Pulak Kumar, Lakshmi J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Dextrose is commonly added to the intraoperative maintenance fluids of pediatric patients. The primary objective was to evaluate the effect of addition of 1% dextrose to Ringer's lactate (RL) on blood glucose levels in infants undergoing facial cleft surgeries. MATERIAL AND METHODS: This prospective, randomized, single blinded study was conducted in forty infants undergoing either cheiloplasty or palatoplasty. Random blood sugar (RBS) was assessed using a glucometer after induction of anaesthesia, and at 1 and 2 hours later. Group R received RL and Group D received RL with 1% dextrose as intraoperative maintenance fluid. Hypoglycemia was defined as RBS <70 mg/dL and hyperglycemia as RBS >150 mg/dL. RESULTS: Baseline RBS levels and those at 60 min and 120 min post-induction were comparable in both groups. The increase in blood sugar levels from baseline to 60 min and to 120 min in each group was significant. Incidence of hyperglycemia was comparable in both groups. There were no episodes of hypoglycemia, intraoperatively. CONCLUSION: Use of Ringer lactate alone or with addition of 1% dextrose resulted in comparable intraoperative blood sugar levels when used as maintenance fluid in infants undergoing facial cleft surgeries. Wolters Kluwer - Medknow 2020 2020-06-15 /pmc/articles/PMC7480286/ /pubmed/33013028 http://dx.doi.org/10.4103/joacp.JOACP_318_18 Text en Copyright: © 2020 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Rajan, Sunil
Barua, Kaushik
Tosh, Pulak
Kumar, Lakshmi
Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title_full Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title_fullStr Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title_full_unstemmed Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title_short Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
title_sort is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480286/
https://www.ncbi.nlm.nih.gov/pubmed/33013028
http://dx.doi.org/10.4103/joacp.JOACP_318_18
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