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Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?

Delayed Cerebral Ischemia (DCI) is a major contributor to morbidity and mortality after SAH. Currently the prevention of vasospasm and DCI relies on nimodipine administration and on maintaining an adequate cerebral perfusion pressure. We report a patient with initial DCI after SAH in which stellate...

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Autores principales: Bortolato, Andrea, Simonato, Davide, Feltracco, Paolo, Munari, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480307/
https://www.ncbi.nlm.nih.gov/pubmed/33013046
http://dx.doi.org/10.4103/joacp.JOACP_251_19
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author Bortolato, Andrea
Simonato, Davide
Feltracco, Paolo
Munari, Marina
author_facet Bortolato, Andrea
Simonato, Davide
Feltracco, Paolo
Munari, Marina
author_sort Bortolato, Andrea
collection PubMed
description Delayed Cerebral Ischemia (DCI) is a major contributor to morbidity and mortality after SAH. Currently the prevention of vasospasm and DCI relies on nimodipine administration and on maintaining an adequate cerebral perfusion pressure. We report a patient with initial DCI after SAH in which stellate ganglion block (SGB) was performed after nimodipine administration. Firstly the procedure was characterized by a iv and intra-arterial nimodipine administration which did not result into a normal perfusion pattern. Therefore a single-shot stellate ganglion block was performed, as suggested in literature. Because of the not sufficient but promising perfusion improvement, we decided to deliver a continuous ganglion block (cSGB) for 5 days. Consequently a further improvement of the cerebral perfusion on CTPerfusion and Real Time Angiographic Perfusion Assessment was registered. In order to treat cerebral vasospasm, SGB is known to be a further valuable treatment, despite its temporary effect. However the continuous use of SGB during initial DCI has never been described before.
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spelling pubmed-74803072020-10-02 Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy? Bortolato, Andrea Simonato, Davide Feltracco, Paolo Munari, Marina J Anaesthesiol Clin Pharmacol Case Report Delayed Cerebral Ischemia (DCI) is a major contributor to morbidity and mortality after SAH. Currently the prevention of vasospasm and DCI relies on nimodipine administration and on maintaining an adequate cerebral perfusion pressure. We report a patient with initial DCI after SAH in which stellate ganglion block (SGB) was performed after nimodipine administration. Firstly the procedure was characterized by a iv and intra-arterial nimodipine administration which did not result into a normal perfusion pattern. Therefore a single-shot stellate ganglion block was performed, as suggested in literature. Because of the not sufficient but promising perfusion improvement, we decided to deliver a continuous ganglion block (cSGB) for 5 days. Consequently a further improvement of the cerebral perfusion on CTPerfusion and Real Time Angiographic Perfusion Assessment was registered. In order to treat cerebral vasospasm, SGB is known to be a further valuable treatment, despite its temporary effect. However the continuous use of SGB during initial DCI has never been described before. Wolters Kluwer - Medknow 2020 2020-06-15 /pmc/articles/PMC7480307/ /pubmed/33013046 http://dx.doi.org/10.4103/joacp.JOACP_251_19 Text en Copyright: © 2020 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bortolato, Andrea
Simonato, Davide
Feltracco, Paolo
Munari, Marina
Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title_full Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title_fullStr Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title_full_unstemmed Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title_short Continuous stellate ganglion block in delayed cerebral ischemia: A possible supplementary approach to traditional therapy?
title_sort continuous stellate ganglion block in delayed cerebral ischemia: a possible supplementary approach to traditional therapy?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480307/
https://www.ncbi.nlm.nih.gov/pubmed/33013046
http://dx.doi.org/10.4103/joacp.JOACP_251_19
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